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Difference between hypothyroid and hyperthyroid

Main difference :


In simple word, hyperthyroidism is increased levels of thyroid hormones and in another case, hypothyroidism is decreased levels of thyroid hormones.

 Let we check out some other differences one by one below :

Difference between hypothyroid and hyperthyroid : 

  • In hyperthyroidism, heart rate is low where in case of hypothyroidism heart rate is high. 
  • Cardiac contractility and cardiac output are low in hypothyroid where both are high in the case of hyperthyroid.
  • Peripheral vascular resistance is high in hypothyroid where peripheral vascular resistance is low in the case on hyperthyroid.
  • Renal blood flow is low in the case of hypothyroid where it is high in hyperthyroid. 
  • Hyperthyroidism can lead to thyrotoxicosis and grave’s disease whereas hypothyroidism does not produce those diseases.
  • Metabolism is faster in hyperthyroidism as compare to hypothyroidism. 
  • Hypothyroidism is treated by supplements of thyroid hormones while hyperthyroidism is treated by anti-thyroid drugs.
  • In hypothyroidism level of T3 and T4 decreased and TSH level increased while hyperthyroidism level of T3 and T4 increased and TSH level decreased. 
  • B-adrenergic receptors in kidney, RAAS activity and filtration pressure are increased in hyperthyroid while all are decreased in case of hypothyroid.
  • In both thyroid urinary concentrating ability is low. 
  • Tubuloglomerular feedback and tubular mass both are high in case of hyperthyroidism while both are low in case of hypothyroidism. 
  • Na/K ATPase and NHE activity are high in hyperthyroid while low in hypothyroid.  
Symptoms of hyperthyroidism :
  • Feeling wired 
  • Itchy red skin 
  • Shakiness
  • Racing heartbeat
  • Feeling hot frequently
  • Hair loss
  • Bowel movements more frequent than usual 
Symptoms of hypothyroidism :
  • Fatigue
  • Depression problem 
  • Hair loss is too common 
  • Dry hair and skin 
  • Goitre 
  • Slow heart rate
  • Irregular period
  • Constipation 
  • Weight gain abruptly 
  • Muscle cramps 
  • Swelling of the thyroid gland 
  • Brittle nails 
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